Intravenous Lidocaine in Bariatric Surgery.

Summary

Although peroperative intravenous lidocaine has been shown to be useful in early recovery after colorectal surgery, its beneficial effect on the specific population of obese patients scheduled for bariatric surgery remained unknown. Investigators hypothesized that peroperative intravenous lidocaine could decrease postoperative opioid consumption and improve postoperative recovery

Timeline

Start

2017-12-01

Primary completion

2019-02-01

Completion

2019-05-01

Outcome

Met primary endpoint

paper difference between medians (95%CI): 1.7 (0.6-3.4) mg; p = 0.004). PMID 32564365 ↗

Publications

• Results Plass F, Nicolle C, Zamparini M, Al Issa G, Fiant AL, Le Roux Y, Gerard JL, Fischer MO, Alves A, Hanouz JL. Effect of intra-operative intravenous lidocaine on opioid consumption after bariatric surgery: a prospective, randomised, blinded, placebo-controlled study. Anaesthesia. 2021 Feb;76(2):189-198. doi: 10.1111/anae.15150. Epub 2020 Jun 21.

Drugs

Indications