Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

Phase 4 Recruiting 100 enrolled Weill Medical College of Cornell University

NaSingle-groupOpen-labelDiagnostic

Summary

Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachycardia.

Timeline

Start: 2017-02-13
Primary completion: 2027-12-31
Completion: 2027-12-31

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Adenosine	Small molecule	0.84 mg/kg	Intravenous
Subject	Verapamil	Other / unclassified	0.15 mg/kg	Intravenous

Indications

No indication recorded.