drugset / Trial / NCT03236727

SSEP Fluctuations Due to Dexmedetomidine During Posterior Spine Fusion

NCT03236727

Phase 3 Completed 25 enrolled George Papanicolaou Hospital
Non-randomizedCrossoverOpen-labelSupportive care

Summary

Intravenous anesthetic agents as far as inhaled agents produce a dose depended increase in latency and decrease in amplitude of SomatoSensory Evoked Potential (SSEP). Dexmetedomidine, a highly selective a2 adrenergic agonist, not only minimizes the anesthetic agents but also the opioids, reducing the analgesic demands. The effect of dexmedetomidine on SSEP has not been elucidated. We aimed to investigate alterations on somatosensory SSEP in adults during posterior spinal fusion surgery before and after Dexmedetomidine administration.

Timeline

Start
2014-03
Primary completion
2016-05
Completion
2016-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 0.7 ug/kg

Indications

No indication recorded.