drugset / Trial / NCT03236740
OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is undertaken to compare the effects of treatment with commonly used OCP containing ethinylestradiol-cyproterone acetate and metformin in women with PCOS. Special attention will be paid to changes in ovarian stromal blood flow by using Color Doppler and they will be correlated with changes in hormonal parameters post-treatment.
Timeline
- Start
- 2017-08-01
- Primary completion
- 2018-03-01
- Completion
- 2018-03-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metformin | Small molecule | 500 mg | — |
| Comparator | cyproterone acetate | Small molecule | 2 mg | Oral |
| Comparator | ethinyl estradiol | Small molecule | 35 ug | Oral |