drugset / Trial / NCT03237442

Umbilical Cord Mesenchymal Stem Cells Injection for Ocular Corneal Burn

NCT03237442

RandomizedParallel-groupDouble-blindTreatment

Summary

Ocular chemical burn is one of the causes of vision loss in China, and there are no satisfactory treatment. Human umbilical cord mesenchymal stem cells(UC-MSCs) have the biological characteristics of self-renewal, immune regulation, multidirectional differentiation and tissue repair. Our preliminary research showed that in corneal alkali injury rabbits, the UC-MSCs can accelerated the cornea repair, inhibited angiogenesis. The aim of this study is to access the efficacy and safety of UC-MSCs in the treatment of corneal burn in human.

Timeline

Start
2018-01-01
Primary completion
2018-12-30
Completion
2019-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject human umbilical cord mesenchymal stem cells Cell therapy 0.2 ml Other
Subject human umbilical cord mesenchymal stem cells Cell therapy 2e+06 cells Other

Indications