human umbilical cord mesenchymal stem cells
Trials 95 · started per year
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/2 | NCT04093336 Comparator | Jan 2019 → Dec 2024 | anterior cerebral artery infarction, middle cerebral artery infarction, posterior cerebral artery infarction | Shanghai East Hospital | Unknown | No outcome recorded |
| Phase 1/2 | NCT02635464 Comparator | Oct 2015 → Aug 2019 | myocardial ischemia | Chinese Academy of Sciences | Completed | No outcome recorded |
Evidence & citations 40 cited values
Every value below carries the sentence it was read from. 110 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | human umbilical cord mesenchymal stem cells | “Human umbilical cord mesenchymal stem cells (UC-MSCs) are multifunctional stem cells with properties such as self-renewal, multidirectional differentiation potential, tissue...” NCT06862388 ↗41“The Safety and Efficacy Assessment of Collagen Membrane Combined With Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Patients With Nasal Septum Perforation” NCT02947191 ↗ “Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosis” NCT03826433 ↗ “Human umbilical cord mesenchymal stem cells improve liver function and ascites in decompensated liver cirrhosis patients.” PMID 22320928 ↗ Mar 2012 “Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Women With Primary Ovarian Insufficiency (POI)” NCT03033277 ↗ “allogeneic human umbilical cord mesenchymal stem cells (hUC-MSCs) in collagen scaffold injecting in the infarct region.” NCT02635464 ↗ “Human umbilical cord mesenchymal stem cells were transplanted by intravenous infusion” NCT03816852 ↗ “human umbilical cord mesenchymal stem cells (hUC-MSCs) transplantation” NCT06589271 ↗ “human umbilical cord mesenchymal stem cells (hUC-MSCs) injection” NCT07183761 ↗ “Human umbilical cord mesenchymal stem cells (hUC-MSC)” NCT06731192 ↗ “Human Umbilical Cord Mesenchymal Stem Cells Injection” NCT07413978 ↗ |
| Known as | 19#iSCLife-LC | “Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosis” NCT03826433 ↗ |
| Known as | aCell Inj. | “A Clinical Trial to Evaluate the Safety, Tolerance and Efficacy of aCell Inj. of Allogeneic UC-MSCs in Patients With Decompensated Hepatitis B Cirrhosis” NCT05948982 ↗ |
| Known as | Cellistem | “Patients with heart failure and reduced ejection fraction under optimal medical treatment were randomized to intravenous infusion of allogenic UC-MSCs (Cellistem, Cells for...” PMID 28974553 ↗ Sep 2017 |
| Known as | Hu-MSCs | “The aim of the study was to examine treatment of cerebral hemorrhages with bone-marrow or human umbilical cord-derived mesenchymal stem cells (BMSCs or Hu-MSCs) and...” PMID 28101148 ↗ Oct 20161“Platelet-rich plasma (PRP) combined with human umbilical cord mesenchymal stem cells (huMSCs)” NCT06302582 ↗ |
| Known as | hUC Mesenchymal Stem Cells | “hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis” NCT03826433 ↗ |
| Known as | HUC-MSC | “The volunteers of the experimental group will be given peripheral intravenously a dose of 1.5\*10\^6/kg human umbilical cord mesenchymal stem cell (HUC-MSC) at 0,8,16,24,32 week.” NCT04216849 ↗6“OBJECTIVE: We evaluate the efficacy of human umbilical cord-derived mesenchymal stem cell (hUC-MSC) for the treatment of lupus nephritis (LN).” PMID 28478399 ↗ May 2017 “human umbilical cord mesenchymal stem cell(hUC-MSC) for cerebral hemorrhage sequela” NCT02283879 ↗ |
| Known as | hUC-MSCs | “Human umbilical cord mesenchymal stem cells (hUCMSCs) and human cord blood mononuclear cells (hCBMNCs) have been shown to have the ability to modulate the immune response and...” NCT01443689 ↗26“Human umbilical cord mesenchymal stem cells (hUC-MSCs) and human cord blood mononuclear cells (hCB-MNCs) have been shown to have the ability to modulate the immune response and...” NCT01343511 ↗ “Human umbilical cord mesenchymal stem cells (hUC-MSCs) have been evidenced to improve motor function, increase muscle strength and reduce abnormal levels of related enzymes” NCT01610440 ↗ “The collection of human umbilical cord derived mesenchymal stem cells (hUC-MSCs) is non-invasive and there are no medical ethics issues in obtaining them.” NCT05962762 ↗ “Human Umbilical Cord Mesenchymal Stem Cell Injection (hUCMSCs) in the Treatment of Patients With Moderate to Severe Systemic Lupus Erythematosus” NCT07041801 ↗ “single dose of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) in patients with severe BPD.” PMID 37223507 ↗ Feb 2022 “human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) combined with platelet-rich plasma (PRP)” NCT06302582 ↗ “allogeneic human umbilical cord mesenchymal stem cells (HucMSCs or MSCs used in the following section)” NCT04093336 ↗ “intramyocardial delivery of human umbilical cord-derived mesenchymal stromal cells (HUC-MSCs)” PMID 32840230 ↗ Nov 2020 “human umbilical cord mesenchymal stem cells (hUC-MSCs) transplantation” NCT06589271 ↗ “human umbilical cord mesenchymal stem cells (hUC-MSCs) injection” NCT07183761 ↗ “Human umbilical cord mesenchymal stem cells（HUC-MSCs）” NCT04314011 ↗ |
| Known as | human UC-MSCs | “human UC-MSCs: 0.2ml(about 2\*10\^6 cells) subconjunctival injection” NCT03237442 ↗ |
| Known as | human umbilical cord -derived mesenchymal stem cells | “The study is designed to assess the safety and efficacy of allogeneic human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) with injectable collagen scaffold...” NCT02635464 ↗5“The Safety and Efficacy Assessment of Injectable Collagen Scaffold™ Combined With Human Umbilical Cord-derived Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Patients...” NCT02786017 ↗ “This is a follow-up study to investigate the long-term safety and efficacy of human umbilical cord -derived mesenchymal stem cells (hUC-MSCs), for the treatment of BPD in...” NCT03873506 ↗ “single dose of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) in patients with severe BPD.” PMID 37223507 ↗ Feb 2022 “human umbilical cord -derived mesenchymal stem cells (hUC-MSCs)” NCT03774537 ↗ “Human Umbilical Cord-derived Mesenchymal Stem Cells (HUC-MSCs)” NCT02745808 ↗ |
| Known as | human umbilical cord mesenchymal stem cell | “Human umbilical cord mesenchymal stem cell transplantation for the treatment of acute-on-chronic liver failure: protocol for a multicentre random double-blind placebo-controlled trial.” PMID 38925694 ↗ Jun 2024 |
| Known as | Human Umbilical Cord Mesenchymal Stem Cell Injection | “The test drug used in this study is called Human Umbilical Cord Mesenchymal Stem Cell Injection” NCT05948982 ↗ |
| Known as | human umbilical cord MSC | “Allogeneic human umbilical cord MSCs will be transplanted” NCT02323477 ↗ |
| Known as | human umbilical cord MSC injection | “The infusion route of human umbilical cord MSC injection is the peripheral vein” NCT05948982 ↗ |
| Known as | human umbilical cord MSC injections | “The human umbilical cord MSC injections used in this study have been studied by the National Health Care Commission (NHC)/Central Military Commission (CMC) General Directorate...” NCT05948982 ↗ |
| Known as | human umbilical cord MSCs | “Non-clinical and other clinical studies suggest that human umbilical cord MSCs can alter the tissue microenvironment through paracrine mechanisms” NCT05948982 ↗2“Human umbilical cord MSCs are transplanted three times by intravenous infusion(1×10\^6/kg) ,once every week，a total of three times.” NCT02442037 ↗ “human umbilical cord MSCs in the treatment of refractory moderate-to-severe Crohn's disease” NCT05262829 ↗ |
| Known as | human umbilical cord-derived mesenchymal stromal cell | “human umbilical cord-derived mesenchymal stromal cell (hUC-MSC)-laden collagen hydrogel intramyocardial injection” PMID 32910197 ↗ Sep 2020 |
| Known as | human umbilical cord-derived mesenchymal stromal cells | “intramyocardial delivery of human umbilical cord-derived mesenchymal stromal cells (HUC-MSCs)” PMID 32840230 ↗ Nov 2020 |
| Known as | human umbilical cord-derived MSCs | “In this study, we aimed to evaluate the safety and efficacy of intravenous infusion of human umbilical cord-derived MSCs (HUC-MSCs) in patients with aging frailty.” PMID 38679727 ↗ Apr 2024 |
| Known as | MSC | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03795974 ↗ |
| Known as | MSCs | “allogeneic human umbilical cord mesenchymal stem cells (HucMSCs or MSCs used in the following section)” NCT04093336 ↗2“human umbilical cord MSCs in the treatment of refractory moderate-to-severe Crohn's disease” NCT05262829 ↗ “treat POI patients wit human umbilical cord mesenchymal stem cells (MSCs).” NCT03816852 ↗ |
| Known as | UC-MSC | “In this randomized clinical trial, we evaluated 1HMRS measures (N-acetyl aspartate [NAA], choline [Cho], creatine [Cr], myo-inositol [mI], NAA/Cho, and NAA/Cr) within...” PMID 42156830 ↗ May 202631“RATIONALE: Umbilical cord-derived mesenchymal stem cells (UC-MSC) are easily accessible and expanded in vitro, possess distinct properties, and improve myocardial remodeling...” PMID 28974553 ↗ Sep 2017 “The aim of this study is to demonstrate the efficacy of Umbilical Cord-Derived Mesenchymal Stem Cell (UC-MSC) therapy in BA by planning a multicentric randomized controlled trial.” NCT06564740 ↗ “Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with active ulcerative colitis，randomized, single blind, controlled prospective study.” NCT02442037 ↗ “Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with paraquat poisoning induced lung injury” NCT02444858 ↗ “Safety and Tolerance of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Ankylosing Spondylitis” NCT05962762 ↗ “umbilical cord-derived MSCs (UC-MSC) can improve the longer term survival in patients with liver cirrhosis” NCT01220492 ↗ “umbilical cord-derived MSCs (UC-MSCs) treatment three times (at weeks 0, 1 and 2).” PMID 38925694 ↗ Jun 2024 “ucMSC 1 million/kg will be given once a week for 4 week .” NCT07075315 ↗ “umbilical-cord-derived mesenchymal stem cell (UC-MSC)” NCT02439541 ↗ “umbilical-cord-derived mesenchymal stem cell (UC-MSC)” NCT02444455 ↗ “Human Umbilical Cord Mesenchymal Stem Cells (UC-MSC)” NCT06579352 ↗ “Umbilical Cord Mesenchymal Stem Cells (UC-MSC)” NCT05948982 ↗ |
| Known as | UC-MSCs | “This non-randomized, open-label, single center phase I/II trial investigated the safety and efficacy of combined transplantation of human cord blood mononuclear cells (CBMNCs)...” PMID 23978163 ↗ Aug 20138“The trial aimed to evaluate the safety of three intravenous infusions of Umbilical Cord-derived MSCs (UC-MSCs) administered at six-week intervals in patients with heart failure...” PMID 41888108 ↗ Mar 2026 “Human umbilical cord mesenchymal stem cells (UC-MSCs) are multifunctional stem cells with properties such as self-renewal, multidirectional differentiation potential, tissue...” NCT06862388 ↗ “The objectives of this study were to assess the feasibility, efficacy, and potential toxicity of human umbilical cord mesenchymal stem cells (UCMSCs) therapy in patients with SCA.” PMID 23151076 ↗ Feb 2013 “Autologous bone marrow mononuclear cells (BM-MNCs) and allogeneic umbilical cord tissue-derived mesenchymal stem cells (UC-MSCs) under sterile conditions to treat this disease.” NCT03943940 ↗ “Bone-marrow mononuclear cells (BM-MNCs) and umbilical-cord tissue-derived mesenchymal stem cells (UC-MSCs) via its immunomodulatory properties” NCT04501341 ↗ “umbilical cord-derived MSCs (UC-MSCs) treatment three times (at weeks 0, 1 and 2).” PMID 38925694 ↗ Jun 2024 “umbilical cord-derived mesenchymal stromal cells (UC-MSCs)” NCT06145035 ↗ “umbilical cord derived mesenchymal stem cells (UC-MSCs)” NCT02439541 ↗ |
| Known as | UCT-MSC | “This study assessed the safety and efficacy of intrathecal injection of umbilical cord tissue mesenchymal stem cells (UCT-MSC) in individuals with cerebral palsy (CP).” PMID 34362453 ↗ Aug 2021 |
| Known as | UMBILICAL CORD DERIVED MESENCHYMAL STROMAL CELLS | “allogeneic umbilical cord-derived mesenchymal stromal cells (MSCs)” NCT04325594 ↗ |
| Known as | umbilical cord derived MSC | “umbilical cord derived MSC (UC-MSC)” NCT01690247 ↗ |
| Known as | Umbilical Cord Mesenchymal Stem Cell | “Umbilical Cord Mesenchymal Stem Cell (UC-MSC) suspension will be injected into the peribulbar.” NCT05909488 ↗ |
| Known as | Umbilical Cord- Mesenchymal Stem Cell (UC-MSC) | “Umbilical Cord- Mesenchymal Stem Cell (UC-MSC)” NCT07439848 ↗ |
| Known as | Umbilical Cord-derived Mesenchymal Stem Cell | “This study evaluated the safety and efficacy of allogeneic umbilical cord-derived mesenchymal stem cell (UC-MSC) infusion via the intravenous (IV) and intrathecal (IT) routes...” PMID 41277536 ↗ Nov 20253“The aim of this study is to demonstrate the efficacy of Umbilical Cord-Derived Mesenchymal Stem Cell (UC-MSC) therapy in BA by planning a multicentric randomized controlled trial.” NCT06564740 ↗ “Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with active ulcerative colitis，randomized, single blind, controlled prospective study.” NCT02442037 ↗ “Umbilical Cord-derived Mesenchymal Stem Cell (UC-MSC) preparations are suspended in Conditioned Medium (CM) until it reaches a 2 ml volume of cell suspension.” NCT05909488 ↗ |
| Known as | umbilical cord-derived mesenchymal stem cells | “This non-randomized, open-label, single center phase I/II trial investigated the safety and efficacy of combined transplantation of human cord blood mononuclear cells (CBMNCs)...” PMID 23978163 ↗ Aug 2013 |
| Known as | umbilical cord-derived MSCs | “The trial aimed to evaluate the safety of three intravenous infusions of Umbilical Cord-derived MSCs (UC-MSCs) administered at six-week intervals in patients with heart failure...” PMID 41888108 ↗ Mar 20261“umbilical cord-derived MSCs (UC-MSCs) treatment three times (at weeks 0, 1 and 2).” PMID 38925694 ↗ Jun 2024 |
| Known as | umbilical-cord tissue-derived mesenchymal stem cells | “Autologous bone marrow mononuclear cells (BM-MNCs) and allogeneic umbilical cord tissue-derived mesenchymal stem cells (UC-MSCs) under sterile conditions to treat this disease.” NCT03943940 ↗1“Allogeneic umbilical cord tissue-derived mesenchymal stem cells will be given via intravenous infusion” NCT04501341 ↗ |
| Known as | UMC119-01 | “UMC119-01 is ex vivo cultured human umbilical cord tissue-derived mensenchymal stem cells product which is intended for prevention of Bronchopulmonary dysplasia.” NCT03631420 ↗ |
| Known as | UMC119-06 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04206007 ↗ |
| Known as | UMC119-06-05 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04914403 ↗ |
| Known as | UMSC01 | “This is a two-stage Phase IIa, dose escalation followed by randomized, open-label, controlled with standard treatment, parallel-group study to evaluate the efficacy and safety...” NCT06147986 ↗3“UMSC01 cells mixed with normal saline will be administered to patients after the onset of diagnosis of multiple sclerosis.” NCT05532943 ↗ “For animal studies, UMSC01 has been demonstrated its effectiveness for AMI and stroke.” NCT04056819 ↗ |
| Known as | YB-1113 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05494723 ↗ |
| Action | Restore | “Human umbilical cord mesenchymal stem cells therapy performs a role as take the place destroyed cerebral tissue with a stem cells graft.” NCT02580019 ↗ |
| Modality | Cell therapy | “human umbilical cord mesenchymal stem cells transplantation” NCT01342250 ↗ |
| Route | Intravenous | “MSCs are infused intravenously.” NCT01220492 ↗ |