human umbilical cord mesenchymal stem cells
Trials 88 · started per year
News releases announcing trial results or a regulatory action · 4
| Date | Issuer | Release |
|---|---|---|
| 2020-02-03 | Meridigen Biotech Co., Ltd. | Regulatory Meridigen New Stem Cell Drug Continues to Achieve Great Milestones meridigen.com ↗
Currently approved by the US Food and Drug Administration (FDA) on January 14, 2020. |
| 2019-08-12 | Meridigen Biotech Co., Ltd. | Regulatory Rising Beyond the Bar of Special Regulations, Meridigen Launch its Phase 1 Clinical Trial meridigen.com ↗
繼獲得美國FDA通過人體臨床一期許可後，亦獲得台灣食藥署（TFDA）核可進行人體臨床試驗一期，預計將會與雙和醫院合作進行。 |
| 2019-06-05 | Meridigen Biotech Co., Ltd. | Regulatory Extending Ischemic Stroke Golden Hour to 72 Hours, Meridigen Gets USFDA Green Light to New Drug Clinical Trial meridigen.com ↗
Today (June 5th), Meridigen (宣捷細胞生物製藥) announced that the U.S. Food and Drug Administration (USFDA) has approved UMC119-06 (New Mesenchymal Stem Cell drug) entry into clinical trial for ischemic stroke treatment. |
| 2018-05-15 | Meridigen Biotech Co., Ltd. | Regulatory Meridigen New Neonatal Stem Cell Drug Received TFDA Approval for Clinical Trial meridigen.com ↗
UMC119-01, a new drug for infant bronchopulmonary dysplasia treatment, made from neonatal umbilical cord mesenchymal stem cell had been approved by TFDA for Phase I clinical trial. |
All press releases naming this drug 6 releases
| Date | Issuer | Release |
|---|---|---|
| 2024-03-04 | CytoMed Therapeutics Pte Ltd | CytoMed Therapeutics Limited Announces Research Collaboration with Singapore Sengkang General Hospital to Advance Injectable Umbilical Cord-Derived Mesenchymal Stem Cells for Cartilage Diseases and Repair cytomed.sg ↗ |
| 2020-02-11 | Meridigen Biotech Co., Ltd. | New Hope for Novel Coronavirus! Meridigen Develops “Umbilical Cord Mesenchymal Stem Cell Therapy” meridigen.com ↗ |
| 2020-02-03 | Meridigen Biotech Co., Ltd. | Meridigen New Stem Cell Drug Continues to Achieve Great Milestones meridigen.com ↗ |
| 2019-08-12 | Meridigen Biotech Co., Ltd. | Rising Beyond the Bar of Special Regulations, Meridigen Launch its Phase 1 Clinical Trial meridigen.com ↗ |
| 2019-06-05 | Meridigen Biotech Co., Ltd. | Extending Ischemic Stroke Golden Hour to 72 Hours, Meridigen Gets USFDA Green Light to New Drug Clinical Trial meridigen.com ↗ |
| 2018-05-15 | Meridigen Biotech Co., Ltd. | Meridigen New Neonatal Stem Cell Drug Received TFDA Approval for Clinical Trial meridigen.com ↗ |
Evidence & citations 39 cited values
Every value below carries the sentence it was read from. 102 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | human umbilical cord mesenchymal stem cells | “Human umbilical cord mesenchymal stem cells (UC-MSCs) are multifunctional stem cells with properties such as self-renewal, multidirectional differentiation potential, tissue...” NCT06862388 ↗40“The Safety and Efficacy Assessment of Collagen Membrane Combined With Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Patients With Nasal Septum Perforation” NCT02947191 ↗ “Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosis” NCT03826433 ↗ “Human umbilical cord mesenchymal stem cells improve liver function and ascites in decompensated liver cirrhosis patients.” PMID 22320928 ↗ Mar 2012 “Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Women With Primary Ovarian Insufficiency (POI)” NCT03033277 ↗ “allogeneic human umbilical cord mesenchymal stem cells (hUC-MSCs) in collagen scaffold injecting in the infarct region.” NCT02635464 ↗ “Human umbilical cord mesenchymal stem cells were transplanted by intravenous infusion” NCT03816852 ↗ “human umbilical cord mesenchymal stem cells (hUC-MSCs) transplantation” NCT06589271 ↗ “human umbilical cord mesenchymal stem cells (hUC-MSCs) injection” NCT07183761 ↗ “Human Umbilical Cord Mesenchymal Stem Cells Injection” NCT07413978 ↗ |
| Known as | 19#iSCLife-LC | “Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosis” NCT03826433 ↗ |
| Known as | aCell Inj. | “A Clinical Trial to Evaluate the Safety, Tolerance and Efficacy of aCell Inj. of Allogeneic UC-MSCs in Patients With Decompensated Hepatitis B Cirrhosis” NCT05948982 ↗ |
| Known as | Cellistem | “Patients with heart failure and reduced ejection fraction under optimal medical treatment were randomized to intravenous infusion of allogenic UC-MSCs (Cellistem, Cells for...” PMID 28974553 ↗ Sep 2017 |
| Known as | Hu-MSCs | “The aim of the study was to examine treatment of cerebral hemorrhages with bone-marrow or human umbilical cord-derived mesenchymal stem cells (BMSCs or Hu-MSCs) and...” PMID 28101148 ↗ Oct 20161“Platelet-rich plasma (PRP) combined with human umbilical cord mesenchymal stem cells (huMSCs)” NCT06302582 ↗ |
| Known as | hUC Mesenchymal Stem Cells | “hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis” NCT03826433 ↗ |
| Known as | HUC-MSC | “The volunteers of the experimental group will be given peripheral intravenously a dose of 1.5\*10\^6/kg human umbilical cord mesenchymal stem cell (HUC-MSC) at 0,8,16,24,32 week.” NCT04216849 ↗1“human umbilical cord mesenchymal stem cell(hUC-MSC) for cerebral hemorrhage sequela” NCT02283879 ↗ |
| Known as | hUC-MSCs | “Human umbilical cord mesenchymal stem cells (hUCMSCs) and human cord blood mononuclear cells (hCBMNCs) have been shown to have the ability to modulate the immune response and...” NCT01443689 ↗26“Human umbilical cord mesenchymal stem cells (hUC-MSCs) and human cord blood mononuclear cells (hCB-MNCs) have been shown to have the ability to modulate the immune response and...” NCT01343511 ↗ “Human umbilical cord mesenchymal stem cells (hUC-MSCs) have been evidenced to improve motor function, increase muscle strength and reduce abnormal levels of related enzymes” NCT01610440 ↗ “The collection of human umbilical cord derived mesenchymal stem cells (hUC-MSCs) is non-invasive and there are no medical ethics issues in obtaining them.” NCT05962762 ↗ “Human Umbilical Cord Mesenchymal Stem Cell Injection (hUCMSCs) in the Treatment of Patients With Moderate to Severe Systemic Lupus Erythematosus” NCT07041801 ↗ “single dose of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) in patients with severe BPD.” PMID 37223507 ↗ Feb 2022 “human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) combined with platelet-rich plasma (PRP)” NCT06302582 ↗ “allogeneic human umbilical cord mesenchymal stem cells (HucMSCs or MSCs used in the following section)” NCT04093336 ↗ “intramyocardial delivery of human umbilical cord-derived mesenchymal stromal cells (HUC-MSCs)” PMID 32840230 ↗ Nov 2020 “human umbilical cord mesenchymal stem cells (hUC-MSCs) transplantation” NCT06589271 ↗ “human umbilical cord mesenchymal stem cells (hUC-MSCs) injection” NCT07183761 ↗ |
| Known as | human UC-MSCs | “human UC-MSCs: 0.2ml(about 2\*10\^6 cells) subconjunctival injection” NCT03237442 ↗ |
| Known as | Human Umbilical Cord Mesenchymal Stem Cell Injection | “The test drug used in this study is called Human Umbilical Cord Mesenchymal Stem Cell Injection” NCT05948982 ↗ |
| Known as | human umbilical cord MSC | “Allogeneic human umbilical cord MSCs will be transplanted” NCT02323477 ↗ |
| Known as | human umbilical cord MSC injection | “The infusion route of human umbilical cord MSC injection is the peripheral vein” NCT05948982 ↗ |
| Known as | human umbilical cord MSC injections | “The human umbilical cord MSC injections used in this study have been studied by the National Health Care Commission (NHC)/Central Military Commission (CMC) General Directorate...” NCT05948982 ↗ |
| Known as | human umbilical cord MSCs | “Non-clinical and other clinical studies suggest that human umbilical cord MSCs can alter the tissue microenvironment through paracrine mechanisms” NCT05948982 ↗2“Human umbilical cord MSCs are transplanted three times by intravenous infusion(1×10\^6/kg) ,once every week，a total of three times.” NCT02442037 ↗ “human umbilical cord MSCs in the treatment of refractory moderate-to-severe Crohn's disease” NCT05262829 ↗ |
| Known as | Human Umbilical Cord-derived Mesenchymal Stem Cells | “The study is designed to assess the safety and efficacy of allogeneic human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) with injectable collagen scaffold...” NCT02635464 ↗5“The Safety and Efficacy Assessment of Injectable Collagen Scaffold™ Combined With Human Umbilical Cord-derived Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Patients...” NCT02786017 ↗ “This is a follow-up study to investigate the long-term safety and efficacy of human umbilical cord -derived mesenchymal stem cells (hUC-MSCs), for the treatment of BPD in...” NCT03873506 ↗ “single dose of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) in patients with severe BPD.” PMID 37223507 ↗ Feb 2022 “human umbilical cord -derived mesenchymal stem cells (hUC-MSCs)” NCT03774537 ↗ “Human Umbilical Cord-derived Mesenchymal Stem Cells (HUC-MSCs)” NCT02745808 ↗ |
| Known as | human umbilical cord-derived mesenchymal stromal cell | “human umbilical cord-derived mesenchymal stromal cell (hUC-MSC)-laden collagen hydrogel intramyocardial injection” PMID 32910197 ↗ Sep 2020 |
| Known as | human umbilical cord-derived mesenchymal stromal cells | “intramyocardial delivery of human umbilical cord-derived mesenchymal stromal cells (HUC-MSCs)” PMID 32840230 ↗ Nov 2020 |
| Known as | human umbilical cord-derived MSCs | “In this study, we aimed to evaluate the safety and efficacy of intravenous infusion of human umbilical cord-derived MSCs (HUC-MSCs) in patients with aging frailty.” PMID 38679727 ↗ Apr 2024 |
| Known as | MSC | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03795974 ↗ |
| Known as | MSCs | “allogeneic human umbilical cord mesenchymal stem cells (HucMSCs or MSCs used in the following section)” NCT04093336 ↗2“human umbilical cord MSCs in the treatment of refractory moderate-to-severe Crohn's disease” NCT05262829 ↗ “treat POI patients wit human umbilical cord mesenchymal stem cells (MSCs).” NCT03816852 ↗ |
| Known as | UC-MSC | “In this randomized clinical trial, we evaluated 1HMRS measures (N-acetyl aspartate [NAA], choline [Cho], creatine [Cr], myo-inositol [mI], NAA/Cho, and NAA/Cr) within...” PMID 42156830 ↗ May 202630“RATIONALE: Umbilical cord-derived mesenchymal stem cells (UC-MSC) are easily accessible and expanded in vitro, possess distinct properties, and improve myocardial remodeling...” PMID 28974553 ↗ Sep 2017 “The aim of this study is to demonstrate the efficacy of Umbilical Cord-Derived Mesenchymal Stem Cell (UC-MSC) therapy in BA by planning a multicentric randomized controlled trial.” NCT06564740 ↗ “Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with active ulcerative colitis，randomized, single blind, controlled prospective study.” NCT02442037 ↗ “Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with paraquat poisoning induced lung injury” NCT02444858 ↗ “Safety and Tolerance of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Ankylosing Spondylitis” NCT05962762 ↗ “umbilical cord-derived MSCs (UC-MSC) can improve the longer term survival in patients with liver cirrhosis” NCT01220492 ↗ “ucMSC 1 million/kg will be given once a week for 4 week .” NCT07075315 ↗ “umbilical-cord-derived mesenchymal stem cell (UC-MSC)” NCT02444455 ↗ “umbilical-cord-derived mesenchymal stem cell (UC-MSC)” NCT02439541 ↗ “Human Umbilical Cord Mesenchymal Stem Cells (UC-MSC)” NCT06579352 ↗ |
| Known as | UCMSCs | “This non-randomized, open-label, single center phase I/II trial investigated the safety and efficacy of combined transplantation of human cord blood mononuclear cells (CBMNCs)...” PMID 23978163 ↗ Aug 20136“The trial aimed to evaluate the safety of three intravenous infusions of Umbilical Cord-derived MSCs (UC-MSCs) administered at six-week intervals in patients with heart failure...” PMID 41888108 ↗ Mar 2026 “Human umbilical cord mesenchymal stem cells (UC-MSCs) are multifunctional stem cells with properties such as self-renewal, multidirectional differentiation potential, tissue...” NCT06862388 ↗ “The objectives of this study were to assess the feasibility, efficacy, and potential toxicity of human umbilical cord mesenchymal stem cells (UCMSCs) therapy in patients with SCA.” PMID 23151076 ↗ Feb 2013 “Autologous bone marrow mononuclear cells (BM-MNCs) and allogeneic umbilical cord tissue-derived mesenchymal stem cells (UC-MSCs) under sterile conditions to treat this disease.” NCT03943940 ↗ “Bone-marrow mononuclear cells (BM-MNCs) and umbilical-cord tissue-derived mesenchymal stem cells (UC-MSCs) via its immunomodulatory properties” NCT04501341 ↗ “umbilical cord derived mesenchymal stem cells (UC-MSCs)” NCT02439541 ↗ |
| Known as | UCT-MSC | “This study assessed the safety and efficacy of intrathecal injection of umbilical cord tissue mesenchymal stem cells (UCT-MSC) in individuals with cerebral palsy (CP).” PMID 34362453 ↗ Aug 2021 |
| Known as | UMBILICAL CORD DERIVED MESENCHYMAL STROMAL CELLS | “UMBILICAL CORD DERIVED MESENCHYMAL STROMAL CELLS (UC-MSC)” NCT02032446 ↗ |
| Known as | umbilical cord derived MSC | “umbilical cord derived MSC (UC-MSC)” NCT01690247 ↗ |
| Known as | Umbilical Cord Mesenchymal Stem Cell | “Umbilical Cord Mesenchymal Stem Cell (UC-MSC) suspension will be injected into the peribulbar.” NCT05909488 ↗ |
| Known as | umbilical cord tissue-derived mesenchymal stem cells | “Autologous bone marrow mononuclear cells (BM-MNCs) and allogeneic umbilical cord tissue-derived mesenchymal stem cells (UC-MSCs) under sterile conditions to treat this disease.” NCT03943940 ↗1“Allogeneic umbilical cord tissue-derived mesenchymal stem cells will be given via intravenous infusion” NCT04501341 ↗ |
| Known as | Umbilical Cord- Mesenchymal Stem Cell (UC-MSC) | “Umbilical Cord- Mesenchymal Stem Cell (UC-MSC)” NCT07439848 ↗ |
| Known as | Umbilical Cord-derived Mesenchymal Stem Cell | “This study evaluated the safety and efficacy of allogeneic umbilical cord-derived mesenchymal stem cell (UC-MSC) infusion via the intravenous (IV) and intrathecal (IT) routes...” PMID 41277536 ↗ Nov 20253“The aim of this study is to demonstrate the efficacy of Umbilical Cord-Derived Mesenchymal Stem Cell (UC-MSC) therapy in BA by planning a multicentric randomized controlled trial.” NCT06564740 ↗ “Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with active ulcerative colitis，randomized, single blind, controlled prospective study.” NCT02442037 ↗ “Umbilical Cord-derived Mesenchymal Stem Cell (UC-MSC) preparations are suspended in Conditioned Medium (CM) until it reaches a 2 ml volume of cell suspension.” NCT05909488 ↗ |
| Known as | umbilical cord-derived mesenchymal stem cells | “This non-randomized, open-label, single center phase I/II trial investigated the safety and efficacy of combined transplantation of human cord blood mononuclear cells (CBMNCs)...” PMID 23978163 ↗ Aug 2013 |
| Known as | Umbilical Cord-derived MSCs | “The trial aimed to evaluate the safety of three intravenous infusions of Umbilical Cord-derived MSCs (UC-MSCs) administered at six-week intervals in patients with heart failure...” PMID 41888108 ↗ Mar 2026 |
| Known as | UMC119-01 | “UMC119-01 is ex vivo cultured human umbilical cord tissue-derived mensenchymal stem cells product which is intended for prevention of Bronchopulmonary dysplasia.” NCT03631420 ↗ |
| Known as | UMC119-06 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04206007 ↗ |
| Known as | UMC119-06-05 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04893174 ↗ |
| Known as | UMSC01 | “This is a two-stage Phase IIa, dose escalation followed by randomized, open-label, controlled with standard treatment, parallel-group study to evaluate the efficacy and safety...” NCT06147986 ↗3“UMSC01 cells mixed with normal saline will be administered to patients after the onset of diagnosis of multiple sclerosis.” NCT05532943 ↗ “For animal studies, UMSC01 has been demonstrated its effectiveness for AMI and stroke.” NCT04056819 ↗ |
| Known as | YB-1113 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05494723 ↗ |
| Action | Restore | “Human umbilical cord mesenchymal stem cells therapy performs a role as take the place destroyed cerebral tissue with a stem cells graft.” NCT02580019 ↗ |
| Modality | Cell therapy | “human umbilical cord mesenchymal stem cells transplantation” NCT01342250 ↗ |
| Route | Intravenous | “MSCs are infused intravenously.” NCT01220492 ↗ |