drugset / Trial / NCT03816852
The Safety and Efficiency Study of Mesenchymal Stem Cell (19#iSCLife®-POI) in Premature Ovarian Insufficiency
RandomizedParallel-groupDouble-blindTreatment
Summary
Evaluate the safety of human umbilical cord mesenchymal stem cells (hucMSCs) in POI treatment; Evaluate the effective hucMSCs in POI treatment. Compare different infusion mode, meanwhile compare with hormone replacement therapy (HRT) withdrawal, so that assessing the stem cell therapy.
Timeline
- Start
- 2018-10-01
- Primary completion
- 2026-12-31
- Completion
- 2027-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | human umbilical cord mesenchymal stem cells | Cell therapy | 3e+07 cells | Intravenous |
| Subject | human umbilical cord mesenchymal stem cells | Cell therapy | 6e+07 cells | Intravenous |
| Subject | human umbilical cord mesenchymal stem cells | Cell therapy | 9e+07 cells | Intravenous |