drugset / Trial / NCT05532943

Evaluate the Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cells in Patients With Multiple Sclerosis

NCT05532943

Phase 1/2 Recruiting 41 enrolled Ever Supreme Bio Technology Co., Ltd.
RandomizedParallel-groupDouble-blindTreatment

Summary

This study is to identify the safety and efficacy of repeat IV(Intravenous) and IT(Intrathecal) administrations of UMSC01 in patients with MS. While anti-inflammatory drugs are routinely used for the treatment of MS by inhibiting immune responses, their effects on axon remyelination or neuroregeneration are limited. The combined systemic delivery of UCMSCs via intravenous injection and local administration of the cells by IT was to have safety and therapeutic efficacy for patients with MS.

Timeline

Start
2023-09-08
Primary completion
2028-10-31
Completion
2028-10-31

Drugs

EvaluationDrugModalityDoseRoute
Subject human umbilical cord mesenchymal stem cells Cell therapy Intravenous

Indications