drugset / Trial / NCT03238300
Neuroscience-Informed Treatment Development for Adolescent Alcohol Use
Phase 2
Completed
57 enrolled
Medical University of South Carolina
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
RandomizedCrossoverDouble-blindBasic science
Summary
This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement, on brains of youth (ages 15-19) using magnetic resonance imaging (MRI).
Timeline
- Start
- 2017-10-16
- Primary completion
- 2022-03-01
- Completion
- 2022-03-01
Outcome
Missed primary endpoint
registry analysis (superiority test); N-Acetylcysteine vs Placebo; p >0.05 NCT03238300 ↗
registry analysis (superiority test); N-Acetylcysteine vs Placebo Oral Capsule; p >0.05 NCT03238300 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | N-acetylcysteine | Small molecule | 1200 mg | Oral |