drugset / Trial / NCT03251469

Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture

NCT03251469

Phase 2 Unknown 200 enrolled National and Kapodistrian University of Athens
RandomizedParallel-groupDouble-blindPrevention

Summary

The aim of this study is to investigate the hypothesis that single dose of tranexamic acid (TXA) preoperatively will lower blood loss and transfusion rate in elderly patients with hip fractures (intertrochanteric or Subcapital), that will be treated with intramedullary nailing and cemented hemiarthroplasty respectively. After application of inclusion and exclusion criteria, patients will be randomized in two groups. Group 1 will include patients that receive preoperatively single dose of TXA (15mg/kg) and Group 2 will include patients that receive normal saline (control group).

Timeline

Start
2013-01
Primary completion
2017-12
Completion
2018-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tranexamic Acid Small molecule 15 mg/kg Intravenous

Indications

No indication recorded.