drugset / Trial / NCT03251924

A Dose Escalation and Combination Immunotherapy Study to Evaluate BMS-986226 Alone or in Combination With Nivolumab or Ipilimumab in Patients With Advanced Solid Tumors

NCT03251924 ↗

Phase 1/2 Terminated 80 enrolled Bristol-Myers Squibb
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to investigate BMS-986226 administered alone or in combination with nivolumab or ipilimumab.

Timeline

Start
2017-09-01
Primary completion
2021-12-20
Completion
2021-12-20

Outcome

Outcome not reported

Stopped (Business): “Study CA021-002 was terminated because the Sponsor discontinued further development of BMS-986226 due to a change in business objectives. The decision for the study closure was not related to any safety concerns associated with BMS-986226.”

Drugs

EvaluationDrugModalityDoseRoute
Subject BMS-986226 Unknown — Intravenous
Subject Ipilimumab Monoclonal antibody — Intravenous
Subject Nivolumab Monoclonal antibody — Intravenous
Background Tetanus vaccine Vaccine — Intravenous

Indications