drugset
drugset / Trial / NCT03262090

Effect of Dexmedetomidine on the Prevention of Emergence Agitation in Children Undergoing Day Surgery

NCT03262090 ↗

Completed 389 enrolled Guangzhou Women and Children's Medical Center
RandomizedParallel-groupTriple-blindPrevention

Summary

Emergence agitation/delirium (EA/ED) is a common complication in pediatric surgery patients, which increases the risk of developing postoperative airway obstruction and respiratory depression. In infants, there is a high incidence of emergence agitation (EA) after desoflurane anesthesia. The aim of the present preliminary study was to determine the safety and efficacy of of intraoperative infusion of dexmedetomidine (DEX) that would prevent postoperative EA and ED in children undergoing day surgery with desoflurane anesthesia

Timeline

Start
2017-09-18
Primary completion
2019-05-15
Completion
2019-05-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 0.2 ug/kg Intravenous
Comparator Dexmedetomidine Other / unclassified 0.4 ug/kg Intravenous
Comparator Dexmedetomidine Other / unclassified 0.6 ug/kg Intravenous
Comparator Dexmedetomidine Other / unclassified 0.8 ug/kg Intravenous
Comparator Dexmedetomidine Other / unclassified 1 ug/kg Intravenous

Indications

No indication recorded.