drugset / Trial / NCT03262701

Adjunctive Hydrogen Peroxide for Periodontal Therapy

NCT03262701

Phase 4 Terminated 42 enrolled Loma Linda University
RandomizedParallel-groupSingle-blindTreatment

Summary

There have been many adjunctive treatments for the additional clinical benefits to scaling and root planing (SRP) in the treatment of chronic periodontitis. Topical hydrogen peroxide (HP) delivered in a custom fabricated tray has been shown to improve pocket depth (PD) and inflammation. The purpose of this study is to assess the adjunctive treatment outcome of HP gel in custom tray application in individuals with chronic periodontitis receiving SRP. The purpose of this investigator-initiated study is to evaluate and compare the clinical effects of scaling and root planing (SRP) combined with local delivery of 1.7% hydrogen peroxide (HP) gel in customized trays to that of SRP alone.

Timeline

Start
2018-04-02
Primary completion
2021-02-08
Completion
2021-02-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydrogen Peroxide Small molecule 0.75 g Oral

Indications