AMG0103 in Subjects With Chronic Discogenic Lumbar Back Pain

Summary

This clinical trial evaluate the safety, tolerability and exploratory efficacy of targeted single injection of AMG0103 in subject with chronic discogenic lumbar back pain

Timeline

Start

2018-02-26

Primary completion

2021-02-15

Completion

2021-02-15

Publications

• Kato K, Akeda K, Miyazaki S, Yamada J, Muehleman C, Miyamoto K, Asanuma YA, Asanuma K, Fujiwara T, Lenz ME, Nakazawa T, An H, Masuda K. NF-kB decoy oligodeoxynucleotide preserves disc height in a rabbit anular-puncture model and reduces pain induction in a rat xenograft-radiculopathy model. Eur Cell Mater. 2021 Jul 20;42:90-109. doi: 10.22203/eCM.v042a07.

Drugs

Indications