drugset / Trial / NCT03266965

Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach

NCT03266965

NaSingle-groupOpen-labelTreatment

Summary

The histaminergic system is phylogenetically one of the oldest parts of the nervous system but it is a relatively recent discovery. It is involved with several vegetative functions like sleep, attention and learning, feeding and satiety, working memory, cognition, depression, and most of all arousal and energy

Timeline

Start
2018-03-23
Primary completion
2020-08-07
Completion
2020-08-07

Drugs

EvaluationDrugModalityDoseRoute
Subject HISTIDINE Small molecule 250 mg
Subject HISTIDINE Small molecule 500 mg
Subject HISTIDINE Small molecule 1000 mg
Background Carbidopa Unknown 50 mg

Indications