drugset / Trial / NCT03266965
Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach
NaSingle-groupOpen-labelTreatment
Summary
The histaminergic system is phylogenetically one of the oldest parts of the nervous system but it is a relatively recent discovery. It is involved with several vegetative functions like sleep, attention and learning, feeding and satiety, working memory, cognition, depression, and most of all arousal and energy
Timeline
- Start
- 2018-03-23
- Primary completion
- 2020-08-07
- Completion
- 2020-08-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | HISTIDINE | Small molecule | 250 mg | — |
| Subject | HISTIDINE | Small molecule | 500 mg | — |
| Subject | HISTIDINE | Small molecule | 1000 mg | — |
| Background | Carbidopa | Unknown | 50 mg | — |