Progesterone and Doppler in Recurrent Abortion

Phase 4 Unknown 50 enrolled Assiut University

RandomizedParallel-groupOpen-labelPrevention

Summary

Recurrent pregnancy loss is classically defined as the occurrence of three or more consecutive pregnancy loss. The American Society of Reproductive Medicine has recently redefined recurrent pregnancy loss as two or more pregnancy losses. A pregnancy loss is defined as a clinically-recognized pregnancy means that the pregnancy has been visualized on an ultrasound or that pregnancy tissue was identified after a pregnancy loss.

Timeline

Start: 2017-10-01
Primary completion: 2019-08-05
Completion: 2019-12-05

Publications

Background Macklon NS, Geraedts JP, Fauser BC. Conception to ongoing pregnancy: the 'black box' of early pregnancy loss. Hum Reprod Update. 2002 Jul-Aug;8(4):333-43. doi: 10.1093/humupd/8.4.333.
Background Sotiriadis A, Papatheodorou S, Makrydimas G. Threatened miscarriage: evaluation and management. BMJ. 2004 Jul 17;329(7458):152-5. doi: 10.1136/bmj.329.7458.152. No abstract available.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dydrogesterone	Other / unclassified	40 mg	Oral
Comparator	Progesterone	Other / unclassified	400 mg	Intravenous

Indications

No indication recorded.