Simultaneous Injection of Propofol and Rocuronium in Inducing General Anesthesia

Summary

This study is conducted to evaluate the efficacy of simultaneous injection of propofol and rocuronium in inducing general anesthesia.

Timeline

Start

2017-08-23

Primary completion

2018-01-30

Completion

2018-01-30

Outcome

Met primary endpoint

paper The average of mask VTs measured at 10, 20, 30, 40, 50, and 60 seconds after apnea was larger in the early rocuronium group PMID 30768462 ↗

paper mean difference, 160 mL breath; 95% CI, 98-221 mL breath; P < .001, unpaired t test PMID 30768462 ↗

Publications

• Min SH, Im H, Kim BR, Yoon S, Bahk JH, Seo JH. Randomized Trial Comparing Early and Late Administration of Rocuronium Before and After Checking Mask Ventilation in Patients With Normal Airways. Anesth Analg. 2019 Aug;129(2):380-386. doi: 10.1213/ANE.0000000000004060.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Propofol	Small molecule	2 unknown	—
Subject	Rocuronium	Other / unclassified	0.6 mg/kg	Intravenous

Indications

No indication recorded.