drugset / Trial / NCT03279341
Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects
RandomizedCrossoverDouble-blindOther
Summary
This study aim was to evaluate the effect of pharmacological treatments normally used to treat functional constipation and in particular PEG, bisacodyl and prucalopride on colonic motility as assessed by high-resolution manometry.
Timeline
- Start
- 2012-12-03
- Primary completion
- 2016-03
- Completion
- 2016-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bisacodyl | Small molecule | 10 mg | Oral |
| Comparator | Prucalopride | Small molecule | 2 mg | Oral |
| Comparator | polyethylene glycol | Other / unclassified | 13.8 g | Oral |