drugset / Trial / NCT03283566
Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT
Phase 2
Completed
9 enrolled
The Cleveland Clinic
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · collabStanford University · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
This will be a pilot, 12-month phase II, open label, randomized, two-arm, single-blinded, placebo-controlled, parallel clinical trial of individuals undergoing TPAIT (Total Pancreatectomy and Autologous Islet Transplantation) for treatment of chronic pancreatitis (CP). The two study arms consist of HCQ-treated (Hydroxychloroquine) and placebo-treated individuals. The purpose of this study is to investigate the effects of HCQ administration compared to placebo on islet cell function post-autologous transplantation.
Timeline
- Start
- 2017-10-03
- Primary completion
- 2020-05-31
- Completion
- 2020-05-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Hydroxychloroquine | Small molecule | 200 mg | — |