drugset / Trial / NCT03284047
Botox for Gummy Smile
Withdrawn
Northwestern University
RandomizedParallel-groupSingle-blindTreatment
Summary
This is a two part study to measure and observe the efficacy of botulinum toxin A for the treatment of gummy smiles. Part A will randomly compare three different doses of botulinum toxin type A (abobotulinumtoxin A) for the treatment of upper anterior gummy smile with larger gingival exposure (\> 4 mm). Part B will assign one of two doses of botulinum toxin type A for participants with smaller gingival exposure (\< 4 mm). Follow-up visits with photography will occur 4 and 12 weeks after their treatment. Subjects currently living in the Chicago metropolitan area and meet inclusion/exclusion criteria will be considered for enrollment. This study is a pilot study designed to determine feasibility of this procedure.
Timeline
- Start
- 2019-04-24
- Primary completion
- 2019-04-24
- Completion
- 2019-04-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 2.5 iu | — |
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 5 iu | — |
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 7.5 iu | — |