drugset / Trial / NCT03284853

Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension

NCT03284853

Phase 3 Completed 436 enrolled Aerie Pharmaceuticals
RandomizedParallel-groupTriple-blindTreatment

Summary

The study is intended to test the effectiveness and safety of Netarsudil / Latanoprost 0.02% / 0.005% Ophthalmic Solution, relative to GANFORT® for lowering of intraocular pressure (IOP) in patients with elevated intraocular pressure

Timeline

Start
2017-09-05
Primary completion
2020-11-06
Completion
2020-11-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bimatoprost Other / unclassified 0.03 % Topical
Subject Latanoprost Small molecule 0.005 % Topical
Subject Netarsudil Small molecule 0.02 % Topical
Comparator Timolol Other / unclassified 0.5 % Topical