drugset / Trial / NCT03290703
A Study to Investigate the Effect of Formulation, Food, and Rabeprazole on the Pharmacokinetics (PK) of GDC-0853 in Healthy Participants
RandomizedCrossoverOpen-labelTreatment
Summary
The purpose of this study is to evaluate the PK of GDC-0853 following changes to formulation and in the presence or absence of food, the proton pump inhibitor (rabeprazole), or both. This will be a 3-part open-label randomized study conducted in healthy adult participants. Approximately 63 subjects will be enrolled in this study.
Timeline
- Start
- 2017-04-18
- Primary completion
- 2018-10-25
- Completion
- 2018-10-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fenebrutinib | Small molecule | — | Oral |
| Subject | Rabeprazole | Small molecule | 20 mg | — |
Indications
No indication recorded.