drugset / Trial / NCT03290963

Effect of Lithium Versus Placebo in Adults With Treatment-Resistant Depression Who Are Receiving Ketamine

NCT03290963

Phase 2 Withdrawn William V. Bobo, M.D.
RandomizedParallel-groupTriple-blindBasic science

Summary

The purpose of this research study is to compare the antidepressant effect of lithium versus placebo in adults receiving ketamine. Lithium is available commercially for depression; ketamine is available commercially and can help the symptoms of depression; however, it has not been approved by the U.S. Food and Drug Administration (FDA) for this use. The FDA has allowed the use of this drug in this research study.

Timeline

Start
2017-11-30
Primary completion
2018-12
Completion
2018-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Lithium Unknown
Comparator Ketamine Small molecule 0.5 mg/kg Intravenous

Indications

No indication recorded.