drugset / Trial / NCT03296800
Study to Evaluate Effects of Probenecid, Rifampin and Verapamil on Bexagliflozin in Healthy Subjects
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to examine the drug-drug interaction when given the study drug, bexagliflozin, with three commonly prescribed medications, probenecid, verapamil or rifampin. The study is to evaluate how safe the study drug is and how well the study drug is tolerated when taken with probenecid, verapamil or rifampin.
Timeline
- Start
- 2017-09-27
- Primary completion
- 2017-12-06
- Completion
- 2017-12-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bexagliflozin | Small molecule | 20 mg | — |
| Subject | Probenecid | Small molecule | 500 mg | — |
| Subject | Rifampin | Small molecule | 600 mg | — |
| Subject | Verapamil | Other / unclassified | 120 mg | — |