drugset / Trial / NCT03299257
Donepezil, Residual Excessive Daytime Sleepiness, Obstructive Sleep Apnea
RandomizedParallel-groupTriple-blindTreatment
Summary
It is a randomized, double-blind, single-center, 30-day study. Patients aged 35-60 years, with apnea and hypopnea index and respiratory disturbance index normalized with CPAP, and Epworth Sleepiness Scale\> 11. Patients undergo baseline and CPAP titration polysomnography, liquor and blood collection, Multiple Sleep Latency Test, anxiety and depression and cognitive assessments.
Timeline
- Start
- 2018-07-06
- Primary completion
- 2018-11-04
- Completion
- 2019-03-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Donepezil | Small molecule | 10 mg | — |