drugset
drugset / Trial / NCT03300648

Treating Brain Swelling in Pediatric Cerebral Malaria

NCT03300648 ↗

Phase 3 Completed 57 enrolled Michigan State University Children's National Research Institute · collabKamuzu University of Health Sciences · collabNational Institute of Allergy and Infectious Diseases (NIAID) · collabNationwide Children's Hospital · collabUniversity of Maryland, Baltimore · collab
RandomizedParallel-groupSingle-blindTreatment

Summary

This study evaluates the effectiveness of two interventions in Malawian children with cerebral malaria at high risk of death. One-third of the participants will receive treatment as usual, one-third will receive treatment as usual and be placed on a mechanical ventilator, and one-third will receive treatment as usual plus intravenous hypertonic saline.

Timeline

Start
2018-01-08
Primary completion
2023-12-31
Completion
2023-12-31

Publications

Drugs

EvaluationDrugModalityDoseRoute
Subject Hypertonic saline Unknown 3 % Intravenous

Indications

cerebral malaria