Compatibility of C7 With Ketogenic Diet in Patients Diagnosed With G1D

Phase 2 Completed 10 enrolled University of Texas Southwestern Medical Center National Institute of Neurological Disorders and Stroke (NINDS) · collab

NaSingle-groupOpen-labelTreatment

Summary

To explore triheptanoin (C7 oil) compatibility with the ketogenic diet by evaluating EEG, and seizure rate, glycemia and ketosis in proven G1D patients receiving a ketogenic diet.

Timeline

Start: 2018-06-05
Primary completion: 2021-06-18
Completion: 2022-07-31

Publications

Results Avila A, Malaga I, Sirsi D, Kayani S, Primeaux S, Kathote GA, Jakkamsetti V, Kallem RR, Putnam WC, Park JY, Shinnar S, Pascual JM. Combination of triheptanoin with the ketogenic diet in Glucose transporter type 1 deficiency (G1D). Sci Rep. 2023 Jun 2;13(1):8951. doi: 10.1038/s41598-023-36001-x.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Triheptanoin	Other / unclassified	45 %	—

Compatibility of C7 With Ketogenic Diet in Patients Diagnosed With G1D

Summary

Timeline

Publications

Drugs

Indications