Drugs / Triheptanoin
Triheptanoin
also known as
UX007 · C7 oil · Dermofeel tc 7 · Dojolvi · Dub thg · Heptanoin, tri- · Lanol 37 t · Radiamuls 2375 · +6 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | DOJOLVI | — | 2020-06-30 | fda.gov ↗ |
Trials 31 · a red edge is where a trial was stopped
Also used as a comparator or background therapy in 5 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 24 trials | ||||||
| Phase 2 | NCT02919631 Comparator | Nov 2016 → Jun 2017 | glycogen storage disease V | French National Institute of Health and Medical Research | Completed | No outcome recorded |
| Phase 2 | NCT02453061 Comparator | Jun 2015 → Dec 2019 | Huntington disease | French National Institute of Health and Medical Research | Completed | No outcome recorded |
| Phase 2 | NCT02432768 Comparator | Apr 2015 → Apr 2018 | glycogen storage disease V | Rigshospitalet, Denmark | Completed | No outcome recorded |
| Phase 2 | NCT02408354 Comparator | Mar 2015 → Apr 2017 | alternating hemiplegia of childhood | French National Institute of Health and Medical Research | Completed | No outcome recorded |
| Phase not stated1 trial | ||||||
| — | NCT03773770 Background | — | disorder of fatty acid oxidation and ketogenesis | Ultragenyx Pharmaceutical Inc | Available | No outcome recorded |
Evidence & citations 18 cited values
Every value below carries the sentence it was read from. 37 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Triheptanoin | “The purpose of this project is to study the efficacy of triheptanoin oil in patients with GLUT1 deficiency syndrome.” NCT02014883 ↗30 |
| Known as | C7 oil | “Triheptanoin (C7 oil) is a triglyceride of the anaplerotic odd-chain fatty acid heptonate.” NCT02000960 ↗ |
| Known as | Dermofeel tc 7 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | Dojolvi | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | Dub thg | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | Heptanoin, tri- | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | Lanol 37 t | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | Radiamuls 2375 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | SpezialölÒ 107 | “Triheptanoin (SpezialölÒ 107®)” NCT02201368 ↗ |
| Known as | Trienanthoin | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | Triheptanoic glyceride | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | Triheptanoina | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | Triheptanoine | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | Trioenanthoin | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297585 ↗ |
| Known as | UX007 | “This treatment plan is intended for the use of UX007 (triheptanoin) in the treatment of a single patient with Glucose Transporter 1 (GLUT1) Deficiency Syndrome.” NCT02968953 ↗6“Triheptanoin (UX007) is a medium chain triglyceride of three seven-carbon fatty acids (C7), on a glycerol backbone, with a molecular formula of C24H44O6.” NCT02500082 ↗ |
| Action | Restore | “The hypothesis is that triheptanoin will restore deficient energy metabolism in these patients” NCT02500082 ↗ |
| Modality | Other / unclassified | “triheptanoin, a 7 carbon triglyceride” NCT00947960 ↗ |
| Route | Oral | “The trial involves 18 subjects ingesting a diet supplemented with triheptanoin” NCT00947960 ↗ |