drugset / Trial / NCT03308552
Radiotherapy With or Without Concurrent Chemotherapy for Limited Lymphatic Metastasis of Esophageal Cancer - 3JECROG P-02
Phase 3
Unknown
164 enrolled
Chinese Academy of Medical Sciences
Affiliated Hospital of Hebei University · collabAnyang Tumor Hospital · collabFujian Cancer Hospital · collabHebei Medical University Fourth Hospital · collabSichuan Cancer Hospital and Research Institute · collabThe First Affiliated Hospital with Nanjing Medical University · collabTianjin Medical University Cancer Institute and Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This phase III trial is designed to explore a higher radiation dose by using IMRT simultaneous integrated boost technique with or without concurrent chemotherapy for esophageal carcinoma with limited lymph node metastasis.
Timeline
- Start
- 2017-12-01
- Primary completion
- 2020-08-30
- Completion
- 2021-08-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cisplatin | Other / unclassified | 20 mg/m2 | — |
| Comparator | Cisplatin | Other / unclassified | 25 mg/m2 | — |
| Comparator | Cisplatin | Other / unclassified | 50 mg/m2 | — |
| Comparator | Cisplatin | Other / unclassified | 80 mg/m2 | — |
| Comparator | Lobaplatin | Small molecule | 20 mg/m2 | — |
| Comparator | Lobaplatin | Small molecule | 25 mg/m2 | — |
| Comparator | Lobaplatin | Small molecule | 50 mg/m2 | — |
| Comparator | Lobaplatin | Small molecule | 50 mg | — |
| Comparator | Lobaplatin | Small molecule | 80 mg/m2 | — |
| Comparator | Nedaplatin | Small molecule | 20 mg/m2 | — |
| Comparator | Nedaplatin | Small molecule | 25 mg/m2 | — |
| Comparator | Nedaplatin | Small molecule | 50 mg/m2 | — |
| Comparator | Nedaplatin | Small molecule | 80 mg/m2 | — |
| Comparator | Paclitaxel | Small molecule | 45 mg/m2 | — |
| Comparator | Paclitaxel | Small molecule | 50 mg/m2 | — |
| Comparator | Paclitaxel | Small molecule | 150 mg/m2 | — |