drugset / Trial / NCT03324425
Simvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast Cancer
NaSingle-groupOpen-labelTreatment
Summary
This study recruits patients with metastatic breast cancer who have progressed on their current regimen of dual anti-HER2 therapy. This study evaluates whether or not the addition of simvastatin to the dual anti-HER2 therapy regimen helps make the tumor respond to the anti-HER2 therapy again. All participants will receive simvastatin in combination with their current anti-HER2 therapy regimen.
Timeline
- Start
- 2020-03-04
- Primary completion
- 2028-12
- Completion
- 2030-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Simvastatin | Small molecule | 80 mg | Oral |