drugset / Trial / NCT03324425

Simvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast Cancer

NCT03324425

Phase 2 Active not recruiting 5 enrolled Baylor Breast Care Center
NaSingle-groupOpen-labelTreatment

Summary

This study recruits patients with metastatic breast cancer who have progressed on their current regimen of dual anti-HER2 therapy. This study evaluates whether or not the addition of simvastatin to the dual anti-HER2 therapy regimen helps make the tumor respond to the anti-HER2 therapy again. All participants will receive simvastatin in combination with their current anti-HER2 therapy regimen.

Timeline

Start
2020-03-04
Primary completion
2028-12
Completion
2030-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Simvastatin Small molecule 80 mg Oral

Indications