drugset / Trial / NCT03326258
Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery
NaSingle-groupOpen-labelTreatment
Summary
This phase Ib/II trial studies the best dose of glembatumumab vedotin when giving together with nivolumab and ipilimumab in treating patients with solid tumor that has spread to other places in the body and cannot be removed by surgery. Monoclonal antibodies, such as glembatumumab vedotin, nivolumab, and ipilimumab, may interfere with the ability of tumor cells to grow and spread.
Timeline
- Start
- 2018-04-20
- Primary completion
- 2018-04-20
- Completion
- 2018-04-20
Outcome
Outcome not reported
Stopped: “The study itself was Disapproved on 04/20/2018 and will not be moving forward.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Glembatumumab Vedotin | Other / unclassified | — | Intravenous |
| Subject | Ipilimumab | Monoclonal antibody | — | Intravenous |
| Subject | Nivolumab | Monoclonal antibody | — | Intravenous |