drugset / Trial / NCT03326258

Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery

NCT03326258

Phase 1/2 Withdrawn National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase Ib/II trial studies the best dose of glembatumumab vedotin when giving together with nivolumab and ipilimumab in treating patients with solid tumor that has spread to other places in the body and cannot be removed by surgery. Monoclonal antibodies, such as glembatumumab vedotin, nivolumab, and ipilimumab, may interfere with the ability of tumor cells to grow and spread.

Timeline

Start
2018-04-20
Primary completion
2018-04-20
Completion
2018-04-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Glembatumumab Vedotin Other / unclassified Intravenous
Subject Ipilimumab Monoclonal antibody Intravenous
Subject Nivolumab Monoclonal antibody Intravenous