Effect of Dexmedetomidine on Renal Function and Delayed Graft Function After Kidney Transplantation

Summary

The purpose of this study is to elucidate the effect of dexmedetomidine on renal function and delayed graft function after kidney transplantation

Timeline

Start

2017-11-01

Primary completion

2019-09-28

Completion

2019-09-28

Outcome

Missed primary endpoint

paper The mean (standard deviation) serum creatinine level on POD 7 was comparable between the groups PMID 34931289 ↗

paper mean difference, 0.05; 95% confidence interval, -0.27 to 0.36; P = 0.77). PMID 34931289 ↗

Publications

• Park JH, Koo BN, Kim MS, Shin D, Kwak YL. Effects of intraoperative dexmedetomidine infusion on renal function in elective living donor kidney transplantation: a randomized controlled trial. Can J Anaesth. 2022 Apr;69(4):448-459. doi: 10.1007/s12630-021-02173-1. Epub 2021 Dec 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexmedetomidine	Other / unclassified	0.4 ug/kg	—

Indications

No indication recorded.