Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride

Summary

In recent years, Berberine hydrochloride has been reported to inhibit cancer cell proliferation and to be cytotoxic towards cancer cells. Patients with familial adenomatous polyposis have a nearly 100 percent risk of colorectal cancer. The aim of this study is to investigate the chemopreventive effects Berberine hydrochlorid on the regression of colorectal adenomas.

Timeline

Start

2017-09-01

Primary completion

2020-08-31

Completion

2021-06-01

Drugs

Indications