drugset / Trial / NCT03337672

Comparison of Dexmedetomidine and Midazolam for Prevention of Emergence Delirium in Children

NCT03337672 ↗

Completed 70 enrolled Eunah Cho, MD
RandomizedParallel-groupTriple-blindPrevention

Summary

Emergence delirium is a common complication in children after anesthesia. The incidence of emergence delirium is reported upto 50%. Prevention of emergence delirium in children is important not only for the patient safety but also for the satisfaction of the parents. Midazolam is the most commonly used medications for prevention of emergence delirium. However, it might lead to delayed awakening from anesthesia and respiratory depression. In this study, the investigators will evaluate whether dexmedetomidine can be effectively and safely administered for prevention of emergence delirium in children compared to midazolam.

Timeline

Start
2017-12-05
Primary completion
2018-12-17
Completion
2018-12-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.3 ug/kg Intravenous
Comparator Midazolam Small molecule 0.03 mg/kg —

Indications