drugset / Trial / NCT03339128

Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

NCT03339128

Phase 2 Recruiting 95 enrolled AbbVie
RandomizedParallel-groupTriple-blindTreatment

Summary

The primary objectives of this study are to explore the therapeutic effect of eluxadoline in treating irritable bowel syndrome with diarrhea (IBS-D) in pediatric participants 6-17 years of age, to evaluate the pharmacokinetics of eluxadoline in pediatric participants with IBS-D, and to evaluate the safety and tolerability of eluxadoline in pediatric participants with IBS-D. Enrollment of 12-17 years old age group is closed, enrollment of the 6-11 years old age group will continue.

Timeline

Start
2017-11-15
Primary completion
2026-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Eluxadoline Small molecule 25 mg Oral
Subject Eluxadoline Small molecule 50 mg Oral
Subject Eluxadoline Small molecule 100 mg Oral