drugset / Trial / NCT03344679

Adenosine and Magnesium Sulphate as Adjuvants for PECS Block.

NCT03344679

Completed 90 enrolled Menoufia University
RandomizedCrossoverDouble-blindOther

Summary

Pectoral nerve block (PECS) has been used for post-operative pain relief in patients undergoing breast surgery. It has been shown that adenosine has an effect on pain modulation. Magnesium sulphate has been used as an adjuvant to local anaesthetics in many nerve block techniques. We hypothesised that adenosine may affect the PECS block quality. We aimed to compare the effect of adding adenosine to the local anaesthetic and compare its effect to magnesium sulphate when used for PECS block.

Timeline

Start
2015-02-01
Primary completion
2017-06-15
Completion
2017-07-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Adenosine Small molecule 12 mg Other
Subject Magnesium Sulfate Other / unclassified 500 mg Other
Background Bupivacaine Other / unclassified 0.25 % Other