drugset / Trial / NCT03344679
Adenosine and Magnesium Sulphate as Adjuvants for PECS Block.
RandomizedCrossoverDouble-blindOther
Summary
Pectoral nerve block (PECS) has been used for post-operative pain relief in patients undergoing breast surgery. It has been shown that adenosine has an effect on pain modulation. Magnesium sulphate has been used as an adjuvant to local anaesthetics in many nerve block techniques. We hypothesised that adenosine may affect the PECS block quality. We aimed to compare the effect of adding adenosine to the local anaesthetic and compare its effect to magnesium sulphate when used for PECS block.
Timeline
- Start
- 2015-02-01
- Primary completion
- 2017-06-15
- Completion
- 2017-07-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Adenosine | Small molecule | 12 mg | Other |
| Subject | Magnesium Sulfate | Other / unclassified | 500 mg | Other |
| Background | Bupivacaine | Other / unclassified | 0.25 % | Other |