drugset / Trial / NCT03349775

Cardiometabolic Disease and Pulmonary Hypertension

NCT03349775

RandomizedParallel-groupQuadruple-blindOther

Summary

This study will investigate if metformin can help people with obesity and high pressures inside their lung blood vessels. Metformin is approved by the U.S. Food and Drug Administration (FDA) to treat diabetes, but metformin is not approved by the FDA to treat pulmonary hypertension. This study will examine whether Metformin will improve the high pressure inside lung blood vessels in people who are obese. The study will help understand the effect of metformin on pressures inside lung blood vessels.

Timeline

Start
2017-11-27
Primary completion
2020-12-22
Completion
2020-12-22

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metformin Small molecule 1 g Oral

Indications