drugset / Trial / NCT03356054

Phase I-II Study in CD30 Positive Diffuse Large B-cell Lymphoma Patients Refractory to First Line Chemotherapy or in First Relapse

NCT03356054

Phase 1/2 Recruiting 37 enrolled HOVON Foundation
NaSingle-groupOpen-labelTreatment

Summary

Patients with CD30 positive DLBCL, primary refractory or in first relapse after R-CHOP or R-CHOP-like therapy will receive brentuximab vedotin in combination with R-DHAP, followed in responsive patients by high dose chemotherapy and ASCT.

Timeline

Start
2018-03-05
Primary completion
2023-01
Completion
2027-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Brentuximab Vedotin Monoclonal antibody