drugset / Trial / NCT03365297
Therapeutics in Active Prostate Cancer Surveillance
NaSingle-groupOpen-labelTreatment
Summary
Testing if short-term use of apalutamide can reduce image defined tumour volumes in men with detectable lesion on multi-parametric Magnetic Resonance Imaging (mpMRI) and being managed by Active Surveillance. The trial will also evaluate the tolerability and side effect profile of men on AS using short term apalutamide and patient acceptability as a therapeutic strategy, as well as determining feasibility of a larger prospective randomised trial of apalutamide.
Timeline
- Start
- 2018-06-05
- Primary completion
- 2019-07-25
- Completion
- 2019-07-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Apalutamide | Small molecule | 240 mg | Oral |