drugset / Trial / NCT03365297

Therapeutics in Active Prostate Cancer Surveillance

NCT03365297

Phase 2 Completed 11 enrolled CCTU- Cancer Theme Janssen-Cilag Ltd. · collab
NaSingle-groupOpen-labelTreatment

Summary

Testing if short-term use of apalutamide can reduce image defined tumour volumes in men with detectable lesion on multi-parametric Magnetic Resonance Imaging (mpMRI) and being managed by Active Surveillance. The trial will also evaluate the tolerability and side effect profile of men on AS using short term apalutamide and patient acceptability as a therapeutic strategy, as well as determining feasibility of a larger prospective randomised trial of apalutamide.

Timeline

Start
2018-06-05
Primary completion
2019-07-25
Completion
2019-07-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Apalutamide Small molecule 240 mg Oral

Indications