drugset / Trial / NCT03377361
An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to investigate treatment with nivolumab in combination with trametinib with or without ipilimumab in participants with previously treated cancer of the colon or rectum that has spread.
Timeline
- Start
- 2018-01-31
- Primary completion
- 2024-11-04
- Completion
- 2024-11-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ipilimumab | Monoclonal antibody | — | — |
| Subject | Nivolumab | Monoclonal antibody | — | — |
| Subject | Regorafenib | Small molecule | — | — |
| Subject | Trametinib | Small molecule | — | — |