(Botox) Mechanisms of Action in Altering the Molecular Environment in Which Pain Fibers Exist

Summary

To compare Botox-treated and Botox-untreated symptomatic tissues (defined as areas where the head hurts and the pain is felt) of chronic migraine (CM) patients using molecular studies.

Timeline

Start

2017-12-01

Primary completion

2023-08-01

Completion

2023-12-01

Outcome

Met primary endpoint

registry analysis (other test); Treatment With OnabotulinumtoxinA Injection vs No Treatment; p <0.0001; t-test, 2 sided NCT03381261 ↗

Drugs

Indications