Postoperative Ibuprofen Use and Risk of Bleeding in Pediatric Tonsillectomy

Summary

Pediatric tonsillectomy is one of the most common surgical procedures annually in the United States; risks include postoperative hemorrhage and poor pain control. Controversy exists regarding optimal pharmacologic pain management following surgery, as each drug's efficacy is balanced by its specific side effects. Ibuprofen is effective in controlling postoperative pain following tonsillectomy, but its mechanism of action results in decreased platelet function, which may increase postoperative bleeding events. This is a multicenter, randomized control non-inferiority trial designed to assess the relationship between short-course ibuprofen use and post-tonsillectomy bleeding when compared to acetaminophen.

Timeline

Start

2018-09

Primary completion

2023-01-01

Completion

2023-01-01

Publications

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Drugs

Indications

No indication recorded.