drugset / Trial / NCT03386474

Study of Safety and Efficacy of Brolucizumab 6 mg Drug Product Intended for Commercialization in Patients With nAMD

NCT03386474

Phase 3 Completed 151 enrolled Novartis Pharmaceuticals
Non-randomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this extension study was to assess the safety and efficacy of the new formulation of brolucizumab 6 mg ophthalmic solution when given to the same patients who received brolucizumab in the core trial CRTH258A2301 (also known as CRTH258-C002). The medical condition treated in the core and extension trials was neo-vascular age-related macular degeneration (nAMD).

Timeline

Start
2018-01-15
Primary completion
2018-09-06
Completion
2018-09-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Brolucizumab Other / unclassified 6 mg Intravitreal
Background Aflibercept Protein / enzyme biologic 2 mg Intravitreal