drugset / Trial / NCT03396211

A Study to Evaluate Apatinib (Also Known as Rivoceranib) Plus Nivolumab in Participants With Unresectable or Metastatic Cancer

NCT03396211

Phase 1 Completed 30 enrolled Elevar Therapeutics
NaSingle-groupOpen-labelTreatment

Summary

This is an open-labeled, single-center, Phase I study to evaluate the safety, tolerability, and efficacy of apatinib with nivolumab treatment in participants with unresectable or metastatic cancer. Total study duration will be approximately 50 months: 12 months of recruitment plus 6 months of treatment and subsequent survival follow up.

Timeline

Start
2017-12-22
Primary completion
2020-10-28
Completion
2022-03-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Nivolumab Monoclonal antibody Intravenous
Subject Rivoceranib Small molecule Oral

Indications