drugset / Trial / NCT03399019

Bispectral Index(BIS) on Depth of Sedation With Dexmedetomidine, Propofol and Midazolam During Spinal Anesthesia

NCT03399019 ↗

Unknown 45 enrolled Hallym University Medical Center
RandomizedParallel-groupTriple-blindOther

Summary

This study is to investigate on the objective relevance between bispectral index (BIS) and Observer's assessment of alertness/sedation (OAA/S) scale in patients sedated with Midazolam, propofol and dexmedetomidine during spinal anesthesia. Also, we will evaluate the reflection of actual sedation levels on BIS monitoring.

Timeline

Start
2016-09-05
Primary completion
2018-03-01
Completion
2018-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.2 ug/kg —
Subject Dexmedetomidine Other / unclassified 0.7 ug/kg —
Comparator Midazolam Small molecule 0.01 mg/kg —
Comparator Midazolam Small molecule 0.05 mg/kg —
Comparator Propofol Small molecule 0.75 mg/kg —
Comparator Propofol Small molecule 3 mg/kg —

Indications

No indication recorded.