drugset / Trial / NCT03400488
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD5718 After Single and Multiple Ascending Dose Administration to Healthy Japanese Men
RandomizedParallel-groupSingle-blindTreatment
Summary
This is a Phase I study to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of the novel compound, AZD5718 in healthy Japanese men. The results from this study will form the basis for decisions on future studies.
Timeline
- Start
- 2018-01-16
- Primary completion
- 2018-06-12
- Completion
- 2018-06-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atuliflapon | Small molecule | 60 mg | Oral |
| Subject | Atuliflapon | Small molecule | 180 mg | Oral |
| Subject | Atuliflapon | Small molecule | 360 mg | Oral |
| Subject | Atuliflapon | Small molecule | 600 mg | Oral |