drugset / Trial / NCT03405584
High Dose of Dual Therapy Plus Bismuth for Helicobacter Pylori Treatment
RandomizedParallel-groupSingle-blindTreatment
Summary
Dual therapy for Helicobacter Pylori including a proton pump inhibitor (PPI) and amoxicillin. Amoxicillin has low resistance rate as well as low percentage of side effects. No trial has examined the the efficacy of high dose of dual therapy plus bismuth for H. pylori treatment.This study is designed to evaluate the efficacy and safety of the addition of bismuth to high dose of dual therapy for H. pylori eradication.
Timeline
- Start
- 2018-01-03
- Primary completion
- 2018-11-02
- Completion
- 2018-11-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bismuth Potassium Citrate | Unknown | 600 mg | — |
| Background | Amoxicillin | Other / unclassified | 1 g | — |
| Background | Esomeprazole | Small molecule | 40 mg | — |