Adjuvant Immunotherapy After Salvage Surgery in Head and Neck Squamous Cell Carcinoma

Summary

Two randomized trials of reirradiation after salvage surgery have been conducted by the GETTEC and GORTEC collaborative groups, both members of the French HN Intergroup: The first trial compared reirradiation and a "wait and see attitude" and was published in 2008 \[1\]. The second trial compared two modalities of reirradiation. Our hypothesis is that adjuvant treatment with immunotherapy will lead to a DFS similar to that observed in previous trials of post-operative reirradiation with possibly lower toxicity.

Timeline

Start

2018-02-12

Primary completion

2027-11

Completion

2027-11

Drugs

Indications