drugset / Trial / NCT03408652

Efficacy and Safety of Systemic Treatments of Bone Metastases From Kidney Cancer in Patients Treated With Targeted Therapies

NCT03408652

Phase 3 Terminated 1 enrolled Centre Leon Berard
RandomizedParallel-groupOpen-labelSupportive care

Summary

Multicenter, randomized, open-label, 2-arm, parallel-group, phase III study whose goal is to assess the efficacy and safety profile of bone-targeted treatments (Arm A: denosumab or zoledronic acid) versus the control arm (Arm B: no specific treatment) in patients with bone metastases under targeted therapy for Metastatic Renal Cell Carcinoma.

Timeline

Start
2019-03-15
Primary completion
2020-06-22
Completion
2020-06-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Denosumab Monoclonal antibody 120 mg Subcutaneous
Subject Zoledronic acid Other / unclassified 4 mg Intravenous

Indications