drugset / Trial / NCT03408652
Efficacy and Safety of Systemic Treatments of Bone Metastases From Kidney Cancer in Patients Treated With Targeted Therapies
RandomizedParallel-groupOpen-labelSupportive care
Summary
Multicenter, randomized, open-label, 2-arm, parallel-group, phase III study whose goal is to assess the efficacy and safety profile of bone-targeted treatments (Arm A: denosumab or zoledronic acid) versus the control arm (Arm B: no specific treatment) in patients with bone metastases under targeted therapy for Metastatic Renal Cell Carcinoma.
Timeline
- Start
- 2019-03-15
- Primary completion
- 2020-06-22
- Completion
- 2020-06-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Denosumab | Monoclonal antibody | 120 mg | Subcutaneous |
| Subject | Zoledronic acid | Other / unclassified | 4 mg | Intravenous |