Influences of Angiotensin-neprilysin Inhibition on Sympathetic Activity in Heart Failure

Summary

The autonomic nervous system plays an important role in controlling the circulation. Increased sympathetic activity has detrimental effects in patients with heart failure. The purpose of this study is to test the hypothesis that combined angiotensin receptor + neprilysin inhibition results in lower sympathetic activity than angiotensin receptor inhibition alone.

Timeline

Start

2017-12-14

Primary completion

2018-09-06

Completion

2018-09-06

Outcome

Outcome not reported

Stopped (Enrollment): “Difficulties in recruiting patients”

Drugs

Indications